Thursday, May 21, 2026
Tuesday, May 19, 2026
Saturday, May 16, 2026
Cancer Mystery Solved: Scientists Discover How Melanoma Becomes “Immortal”
Every time a healthy cell divides, its telomeres become slightly shorter. Scientists often compare telomeres to the plastic tips on shoelaces because they help protect chromosomes from fraying or breaking apart.
Eventually, telomeres shrink to a critical length, triggering a process called replicative senescence. At that point, the cell can no longer divide. This natural limit acts as one of the body’s important defenses against cancer.
Tumors must bypass that barrier to survive.
Many cancers accomplish this by reactivating telomerase, an enzyme that rebuilds telomeres and extends a cell’s lifespan. In melanoma, mutations in the TERT gene, which produces telomerase, are especially common. About 75% of melanoma tumors carry these mutations.
But there was a puzzle researchers could not explain.
Eventually, telomeres shrink to a critical length, triggering a process called replicative senescence. At that point, the cell can no longer divide. This natural limit acts as one of the body’s important defenses against cancer.
Tumors must bypass that barrier to survive.
Many cancers accomplish this by reactivating telomerase, an enzyme that rebuilds telomeres and extends a cell’s lifespan. In melanoma, mutations in the TERT gene, which produces telomerase, are especially common. About 75% of melanoma tumors carry these mutations.
But there was a puzzle researchers could not explain.
How Much Protein Do You Really Need?
https://www.consumerreports.org/health/nutrition-healthy-eating/how-much-protein-do-you-really-need-a2065027197/
From the article I calculate that I should eat 5.67 ounces of protein per day. I don't nornally read food labels for the protein content, but now I am curious.
Tuesday, May 12, 2026
The Most Impressive Anti-Aging Supplement
https://www.youtube.com/watch?v=fauPpkI8Z18
I'm not saying that anyone should buy this, but I decided to order this product...
https://www.amazon.com/MYOXCIENCE-Glycine-Supreme-N-Acetyl-L-Cysteine-Combination/dp/B0BNSY4MRD?th=1
As always, I would like to see more research.
Google AI says the following...
GlyNAC (a combination of Glycine and N-acetylcysteine) is highly beneficial as a strategy for healthy aging, specifically by boosting natural glutathione levels.
Research indicates that as people age, their ability to synthesize glutathione—the body's "master antioxidant"—declines. GlyNAC provides the necessary precursors to restore these levels, which in turn recharges cellular "batteries" (mitochondria) and combats oxidative stress.
Key Health Benefits
Clinical trials and research studies highlight several specific areas of improvement:
- Brain Health & Cognition: Supplementation has been shown to reverse age-associated cognitive decline and support overall brain health in both human and animal models.
- Physical Strength & Mobility: Older adults taking GlyNAC experienced significant improvements in muscle strength, gait speed, and exercise capacity.
- Metabolic Health: Studies found GlyNAC reduces insulin resistance and improves mitochondrial fuel oxidation, which is particularly beneficial for those with type 2 diabetes or metabolic dysfunction.
- Cellular Protection: It reduces chronic inflammation, oxidative stress, and genomic damage (DNA damage), which are key hallmarks of aging.
- Specific Conditions: Benefits have also been observed in patients with HIV, where it helped correct premature aging defects and improved quality of life.
Comparison: GlyNAC vs. Glutathione
Sunday, May 10, 2026
Saturday, May 9, 2026
Why Don't Bugs Enter Hospitals? The $1 Secret They Put In Every Doorway
https://www.youtube.com/watch?v=nGzGVzfbJpI
I don't have an insect problem in my house except I had some ants invade the kitchen. I bought a bottle of ant poison from Walmart and this took care of the ants.
Friday, May 8, 2026
Thursday, May 7, 2026
Wednesday, May 6, 2026
Tuesday, May 5, 2026
Is Fusion power going to connect to grid soon after next year's demonstration?
On Tue, May 5, 2026 at 3:07 PM Larry wrote:
If only we had an enormous ball of hydrogen to generate fusion power.
Solar power is reportedly borderline cost-effective. As fossil fuel reserves decline and likely become more expensive, solar power should become more economical. However, I’m not sure how long this rise in cost will take; it could be decades.
Installing solar panels on your roof can make roof replacement twice as expensive. Panels can also damage or overheat your roof, and storms could damage them as well. I would rather leave that to the power company.
The solar roof tile idea is interesting, but only if there is a shortage of land for solar installations. There is a great deal of surface area on roofs that we could utilize.
Monday, May 4, 2026
Sunday, May 3, 2026
The Disaster I Never Imagined Having To Worry About
https://www.youtube.com/watch?v=ksn5yrsC3Wg
I found this really interesting, but I assume that most people wouldn't want to watch the full 33 minute video.
The bottom line is that the AIDS drug Ritonavir started crystallizing during production making it not useful. This is because chemicals can take different arrangements called polymorphs. Once the process starts, it is impossible to stop because the crystals are self-replicating, and it is not simply a matter of cleaning or replacing all the equipment.
This process could affect many drugs we take. One researcher made it happen with aspirin.
This problem has led to increased medical regulation requiring research on possible polymorphs.
Saturday, May 2, 2026
Friday, May 1, 2026
A Masterclass in Manipulation
0 seconds ago
Hank,
Climate Alarmism has become a religion. I think that it is confirmation bias for the political left because it justifies authoritarian government control over the entire energy sector. It was justification for Biden bragging about shutting down coal plants. This is what the Climate Alarmist Skeptics are afraid of. They don't want authoritarian government. They want free choice.
They also don't want the government spending a trillion dollars of their money to fix the problem until we are sure that it really is a problem. When government provides incentives to do a particular thing, this is a form of coercion because it causes people to make economic decisions that they would have not otherwise made, and at the expense of taxpayers.
The actual temperature changes are not very scary and the public in general senses this. When temperatures are not much different than they were in my childhood 60 years ago, I notice, and so do many other people.
The data shows that it took 140 years for the average atmospheric surface temperature to rise by 1 degree celsius. In short, these changes happen very gradually giving the people and the government plenty of time to adapt if we need to.
Saying we have a large number of record warm days sounds scary, but when those records are by 0.01 or 0.02 degrees, we are clearly being manipulated by graphs that resemble a hockey stick.
Apparently, the somewhat questionable need for massive AI datacenters is causing the country to not worry so much about our energy usage and climate change.
I think that humans have a psychological need to worry about something. The boogey man of the day could be government, corporations, or climate change, but it feels like much ado about nothing.
I always enjoy your videos.
Best wishes,
John Coffey
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