| telomeres |
Weekly update ⋅ September 6, 2017
This is the secret to a longer life
The researchers focused on telomeres, which are proteins found in the cell's nucleus that stabilize the ends of chromosomes. Confused? Let me ...
Researchers at Mayo Clinic's Robert and Arlene Kogod Center on Aging developed the first senolytic drugs to target these harmful cells. In a recent study led by The Scripps Research Institute, Mayo Clinic researchers and others confirmed that the senolytic drugs discovered at Mayo effectively clear senescent cells while leaving normal cells unaffected. The study, which was published in Nature Communications, also describes a new screening platform for finding additional senolytic drugs that will more optimally target senescent cells. The platform, together with additional human cell assays, identified and confirmed a new category of senolytic drugs, which are called HSP90 inhibitors.